The Grover Lab
UNC Blood Research Center
The University of North Carolina at Chapel Hill
ABOUT
Our laboratory's research is aimed at identifying novel mechanisms responsible for pathological activation of coagulation and venous thromboembolism. Venous thromboembolism, including deep vein thrombosis and pulmonary embolism, is a common cardiovascular disease that is a major source of morbidity and mortality worldwide. The mechanisms that drive pathological activation of coagulation and venous thrombosis remain incompletely understood. We contend that a better understanding of these mechanisms will enable identification of at risk populations and novel targets for the development of safe and effective anticoagulants. We are currently exploring the role of C1-inhibitor, an endogenous inhibitor of multiple intrinsic pathway coagulation factors, as an important negative regulator of coagulation and venous thrombosis.
Steven P. Grover, PhD
Research Assistant Professor
Principal Investigator
RESEARCH AREAS
NEWS
05/17/2024: Steven Grover wins the Brinkhous Prize at AHA Vascular Discovery
04/09/2024: The Grover Lab publishes on a FXII independent function of plasma kallikrein in Blood Advances
07/20/2023: The Grover Lab welcomes postdoc Linda Sundler Björkman
06/25/2023: The Grover Lab welcomes postdoc Harish Eswaran
06/28/2023: The Grover Lab presents new research at ISTH in Montreal
06/17/2023: Steven Grover presents at the Massachusetts General Hospital Center for Hematology seminar series
05/11/2023: Our recent publication on C1 inhibitor deficiency and thrombosis has been highlighted in an editorial by David Gailani